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After 12 weeks of treatment with Omvoh, nearly two-thirds (65%) of patients achieved clinical response and nearly one-fourth (24%) achieved clinical remission compared to placebo (43% and 15%, for clinical response and clinical remission, respectively).Prior to initiating therapy with mirikizumab, complete all age-appropriate vaccinations according to current immunization guidelines. a wholly owned subsidiary of Eli Lilly and Company (NYSE: LLY), today announced positive initial clinical results from the Phase 1/2. In October 2023, the US Food and Drug Administration ( FDA) approved Omvoh for treating adults with moderate to severe active UC.

Mirikizumab-mrkz, a humanized immunoglobulin G4 (IgG4) monoclonal antibody, is an interleukin-23 antagonist. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Patients who achieved clinical response at Week 12 with Omvoh in UC-1 were re-randomized 2:1 to receive Omvoh (200 mg) subcutaneous injection or placebo subcutaneous injection every 4 weeks for another 40 weeks in UC-2.Tell your doctor if you have or have ever had TB, if you have lived in a country where TB is common, or if you have been around someone who has TB.